Complement Components C3 & C4Main Content
Test Code: 5704
CPT Code(s): 86160 (x2)
Includes: Complement Component C3C; Complement Component C4C
Clinical Significance: Decreased concentrations of both C3 and C4 suggest activation of the classical pathway, whereas decreased concentration of just C3 suggests activation of the alternative pathway. Both complement factors may be used to monitor activity of patients with systemic lupus erythematosus (SLE) and immune complex-induced vasculitis.
Alternative Name(s): C4 and C3 Complements, C3 and C4 Complements
Supply: T01 - Red/Gray SST 8.5mL
Preferred Specimen: Serum
Preferred Volume: 1mL
Transport Container: Serum Separator Tube (SST)
Transport Temperature: Refrigerated
Specimen Stability: Refrigerated: 4 days
Rejection Criteria: Ambient serum
For additional supply or collection device information, please contact DLO's Customer Service at (800) 891-2917, option 2.
The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the Payor being billed.