HSV 1/2 IgG Specific AntibodyMain Content
Test Code: 6447
CPT Code(s): 86695, 86696
Methodology: Immunoassay (IA)
Clinical Significance: Herpes Simplex Virus (HSV) is responsible for several clinically significant human viral diseases, with severity ranging from inapparent to fatal. Clinical manifestations include genital tract infections, neonatal herpes, meningoencephalitis, keratoconjunctivitis, and gingivostomatitis. There are two HSV serotypes that are closely related antigenically. HSV type 2 is more commonly associated with genital tract and neonatal infections, while HSV type 1 is more commonly associated with infections of non-genital sites. Specific typing is not usually required for diagnosis or treatment. The mean time to seroconversion using the type specific assay is 25 days. The performance of this assay has not been established for use in a pediatric population, for neonatal screening, or for testing of immunocompromised patients
Limitations: Individuals infected with HSV may not exhibit detectable IgG antibody in the early stages of infection.
Alternative Name(s): Not applicable
Supply: 193262 Red/Gray SST 8.5mL
Preferred Specimen: Serum
Preferred Volume: 1mL
Transport Container: Serum Separator Tube (SST)
Transport Temperature: Room Temperature
Specimen Stability: Room Temperature: 7 Days
Rejection Criteria: Plasma; Gross hemolysis; Gross lipemia
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The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the Payor being billed.