Iron, Total and Total Iron Binding Capacity

Supply #193262 Red/Gray SST 8.5mL

Test Code: 7573

CPT Code(s): 83540, 83550

Includes: Total Iron, Iron Binding Capacity, % Saturation (calculated)

Methodology: Spectrophotometry (SP)

Clinical Significance: Serum iron quantification is useful in confirming the diagnosis of iron-deficiency anemia or hemochromatosis. The measurement of total iron binding in the same specimen may facilitate the clinician's ability to distinguish between low serum iron levels caused by iron deficiency from those related to inflammatory neoplastic disorders. The assay for iron measures the amount of iron which is bound to transferrin. The total iron binding capacity (TIBC) measures the amount of iron that would appear in blood if all the transferrin were saturated with iron. It is an indirect measurement of transferrin concentrations but expressed as an iron measurement. To obtain the percent saturation, the serum iron is divided by the TIBC which gives the actual amount of saturated transferrin. The percent saturation is low in iron deficiency and high in iron storage diseases.

Alternative Name(s): N/A

Collection Guide: 

Supply: 193262 Red/Gray SST 8.5mL

Preferred Specimen: Serum

Preferred Volume: 2mL

Transport Container: Serum Separator Tube (SST)

Transport Temperature: Room Temperature

Specimen Stability: Room Temperature: 6 days

SPECIAL INSTRUCTIONS: Samples should be taken in the morning from patients in a fasting state, since iron values decrease by 30% during the course of the day and there can be significant interference from lipemia.

Rejection Criteria: Gross hemolysis, anticoagulants other than heparin

For additional supply or collection device information, please contact DLO's Customer Service at (800) 891-2917, option 2.

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the Payor being billed.