Test Code: 746
CPT Code(s): 84146
Methodology: Immunoassay (IA)
Clinical Significance: During pregnancy and postpartum lactation, serum prolactin can increase 10- to 20-fold. Exercise, stress, and sleep also cause transient increases in prolactin levels. Consistently elevated serum prolactin levels (>30 ng/mL), in the absence of pregnancy and postpartum lactation, are indicative of hyperprolactinemia. Hypersecretion of prolactin can be caused by pituitary adenomas, hypothalamic disease, breast or chest wall stimulation, renal failure or hypothyroidism. A number of drugs, including many antidepressants, are also common causes of abnormally elevated prolactin levels. Hyperprolactinemia often results in galactorrhea, amenorrhea, and infertility in females, and in impotence and hypogonadism in males. Renal failure, hypothyroidism, and prolactin-secreting pituitary adenomas are also common causes of abnormally elevated prolactin levels.
Alternative Name(s): Mammotropin; Chorionic Growth Hormon; Chorionic Growth Hormone, Pediatric; Lactogenic Hormone; Lactogenic Hormone, Pediatric; Mammotropin, Pediatric; PRL; PRL, Pediatric; Prolactin Evaluations; Prolactine w/ Tanner Stages
Supply: T01 - Red/Gray SST 8.5mL
Preferred Specimen: Serum
Preferred Volume: 1mL
Transport Container: Serum Separator Tube (SST)
Transport Temperature: Room Temperature
Specimen Stability: Room Temperature: 5 days
Special Instructions: Overnight fasting is preferred.
Rejection Criteria: Contact DLO's Customer Service for specific criteria.
For additional supply or collection device information, please contact DLO's Customer Service at (800) 891-2917, option 2.
The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the Payor being billed.