Aspartate Aminotransferase (AST)Main Content
Test Code: 822
Methodology: Spectrophotometry (SP)
Clinical Significance: AST is widely distributed throughout the tissues with significant amounts being in the heart and liver. Lesser amounts are found in skeletal muscles, kidneys, pancreas, spleen, lungs, and brain. Injury to these tissues results in the release of the AST enzyme to general circulation. In myocardial infarction, serum AST may begin to rise within 6-8 hours after onset, peak within two days and return to normal by the fourth or fifth day post infarction. An increase in serum AST is also found with hepatitis, liver necrosis, cirrhosis, and liver metastasis.
Alternative Name(s): AST, SGOT
Supply: T01 - Red/Gray SST 8.5mL
Preferred Specimen: Serum
Preferred Volume: 1mL
Transport Container: Serum Separator Tube (SST)
Transport Temperature: Room Temperature
Specimen Stability: Room Temperature: 4 days
Rejection Criteria: Specimens exceeding stability; Unlabeled or improperly labeled specimens; Specimens other than serum; Hemolyzed specimens
For additional supply or collection device information, please contact DLO's Customer Service at (800) 891-2917, option 2.