Alanine Aminotransferase (ALT)

Supply #T01 - Red/Gray SST 8.5mL

Test Code: 823

CPT Code(s): 84460

Includes: AST

Methodology: Spectrophotometry (SP)

Clinical Significance: Alanine Aminotransferase (ALT) measurements are particularly useful in the diagnosis and management of certain liver diseases, e.g., viral hepatitis and cirrhosis. ALT activity in tissue is generally much lower than aspartate aminotransferase (AST) activity and is found in highest concentrations in the liver. Significant elevations of ALT occur only in diseases of the liver. ALT is often measured in conjunction with AST to determine whether the source of the AST is the liver or the heart. ALT is normally not elevated in cases of myocardial infarction, i.e., a normal ALT, in conjunction with an elevated AST, tends to suggest cardiac disease. However, slight elevations of ALT may occur if an infarct destroys a very large volume of heart muscle.

Alternative Name(s): ALT, SGPT

Collection Guide: 

Supply: T01 - Red/Gray SST 8.5mL

Preferred Specimen: Serum

Preferred Volume: 1mL

Transport Container: Serum Separator Tube (SST)

Transport Temperature: Room Temperature

Specimen Stability: Room Temperature: 4 days

Rejection Criteria: Specimens exceeding stability; Unlabeled or improperly labeled specimens; Specimens other than serum

NOTE: The assay manufacturer, Beckman Coulter, warns that patients treated with Sulfalazine may generate false low results for ALT. Trauma to striated muscle, tissue, rhabdomyolysis, polymyositis, and dermatomyositis may produce increased results. Hemolyzed samples may yield elevated results. Some illegal drugs (cocaine, anabolic steroids, ecstasy) may also produce increased results.

For additional supply or collection device information, please contact DLO's Customer Service at (800) 891-2917, option 2.

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the Payor being billed.