Test Code: 5509
Alternative Name(s): Not applicable
Clinical Significance: Ammonia is one of the by-products of protein metabolism. Elevated blood ammonia levels have been associated with severe liver dysfunction such as hepatic encephalopathy, coma resulting from cirrhosis, severe hepatitis, Reye's syndrome and drug hepatotoxicity. Also, elevated blood ammonia has been reported in cardiac failure, azotemia, and pulmonary emphysema. Correlation between plasma ammonia and the degree of encephalopathy can be erratic.
Supply: T02 - Lavender 4mL Blood Tube
Preferred Specimen: Plasma collected in a EDTA (lavender) tube
Preferred Volume: 2mL
Collection Instructions: Collect blood from stasis-free vein of patient (e.g., no tourniquet). Patient should not clench fist during collection, as muscular exertion often increases venous ammonia levels. Patient should avoid smoking prior to phlebotomy since smoking increases plasma ammonia levels. Tubes should be filled completely and kept tightly stoppered at all times. Place immediately on ice. Separate plasma from cells within 15 minutes and freeze plasma immediately.
Transport Container: Transport tube
Transport Temperature: Frozen
Specimen Stability: Frozen at -20C: 72 hours
Reject Criteria: Hemolyis; Received thawed, PPT potassium EDTA (white-top) tube
For additional test, supply, or collection device information, please contact DLO's Customer Service at (800) 891-2917, option 2.