BRCAvantage™ Comprehensive

Supply #T59 - Lavender 4mL Blood Tube

BRCAvantage™ Comprehensive

Test Code: 91863

CPT Code(s): 81162

Supply: 193292 Lavender 4mL Blood Tube

BRCA1 Sequencing, BRCA1 Deletion/Duplication, BRCA2 Sequencing, BRCA2 Deletion/Duplication, Comprehensive Interpretation

Next Generation Sequencing • Multiplex Ligation-dependent Probe Amplification (MLPA)

Reference Range(s): See Laboratory Report

Test FAQ: BRCAvantage Comprehensive

Test Summary: BRCAvantage, Comprehensive

Test Guide: Hereditary Breast Cancer Test Selection Guide

White Paper: Testing Criteria for HBOC Syndrome

Alternative Name(s):
BRCA1 and BRCA2 Comprehensive Panel, BRCA1 Comprehensive Panel, BRCA2 Sequencing, Genetic Breast Cancer, Hereditary Ovarian Cancer, BRCA1 Sequencing, BRCA1 Deletion/Duplication, BRCA1 and BRCA2 Deletion/Duplication, BRCA2 Deletion/Duplication, Hereditary Breast Cancer, BRCA2 Comprehensive Panel

Health Plan Coverage:
We are in-network with most national plans and many local plans

Price and Financial Assistance:
The list price of the BRCAvantage® Comprehensive test is $2,495. The Ashkenazi, Single Site, Single Gene and Rearrangement tests are $500 each. List price for BRCAvantage Plus is $3,300 and $805 without BRCA1 and BRCA2.

We provide an easy to use financial assistance program that limits out of pocket expense to $200 for qualified patients with income at or below 400% of the federal poverty level for qualified tests. For patients who do not qualify, we have 0% interest payments plans to help with the cost of testing. Visit for more details.

Concierge Service:
Our team is committed to helping you and your patients navigate the complexities of insurance reimbursement:

  • Insurance Verification: Upon receipt of a fully completed order and patient specimen, we will verify coverage of your patient’s plan. We will manage this process from beginning to end and take the steps needed for each order. Estimated
  • Patient Responsibility: We will estimate your patient’s likely out-of-pocket responsibility at the same time of insurance verification. If the estimated patient responsibility is more than $350, we will attempt to notify you and/or your patient prior to performing the test.

Genetic Counseling
Our team of genetic counselors is available from 8:30 a.m. to 8:00 p.m. EST by calling 866.GENE.INFO (866-436-3469) to help medical professionals with genetics related questions, including appropriate test selection and interpretation of results. We also connect patients with external genetic counselors as requested and when required by health plans after testing has been ordered.

Collection Guide: 

Ordering and reporting can be done by paper or electronically, using Quanum™ Solutions or other EMR interfaces.

Preferred Specimen 4 mL whole blood in an EDTA Lavender-top 4mL tube

Supply: T59 - Lavender 4mL Blood Tube

Transporting: Samples can be picked up by DLO Route Service Representative or, when this is not available, by FedEx with a prepaid mailer. Store and ship ambient immediately.

Turnaround Time:
10-14 days for BRCAvantage Comprehensive if orderis complete, patient meets criteria, and health plan does not require preauthorization. 7 additional days for BRCAvantage PLUS reflex codes.

Transport Temperature: Room Temperature

Specimen Stability:
  • Room Temperature: 8 Days
  • Refigerated: 8 Days

Reject Criteria:

For additional supply or collection device information, please contact DLO's Customer Service at (800) 891-2917, option 2.

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed.