Primary Care

Lactate Dehydrogenase (LD)

Test Code: 593

CPT Code(s): 83615

Methodology: Spectrophotometry (SP)

Clinical Significance: Elevations in serum lactate dehydrogenase occur from myocardial infarction, liver disease, pernicious and megaloblastic anemia, pulmonary emboli, malignancies, and muscular dystrophy. Since lactic dehydrogenase is present in many body tissues, it's diagnosis usefulness is limited. Tissue specificity may be enhanced by isoenzyme analysis.

Heterophile, Mono Screen

Test Code: 654

CPT Code(s): 86308

Methodology: Agglutination

Clinical Significance: Heterophile antibodies, in patients with infectious mononucleosis, may be present as early as the fourth day of illness, and by the twenty-first day of illness, 90% of patients will exhibit a positive test. The Epstein-Barr virus causes infectious mononucleosis.

Alternative Name(s): Infectious Mononucleosis, Mono Screen


 

BRCAvantage with Reflex to Breast Plus Panel

Breast Plus Panel without BRCA (TP53, STK11, PTEN, CDH1, PALB2)

Test Code: 92586

CPT Code(s): 81321, 81323, 81404, 81405 (x2), 81406 (x2), 81479

Clinical Significance: CDH1, PALB2, PTEN, STK11 and TP53 are tumor suppressor genes, where inherited mutations significantly increase breast cancer risk. Sequence analysis and deletion/duplication analysis of these five genes can explain an additional 3% to 4.5% of hereditary breast cancers.

BRCAvantage with Reflex to Breast Plus Panel

Test Code: 92573

CPT Code(s): 81162

Includes: If the Interpretation Summary is not one of the following three results: Positive for a known Pathogenic Mutation; Positive for a likely Pathogenic Mutation; Positive for a likely Pathogenic Mutation and a variant with unknown significance, then TP53, PTEN, CDH1, STK11, and PALB2 will be performed at an additional charge (CPT code(s) 81321, 81323, 81404, 81405 (x2), 81406 (x2), 81479).