Childhood and Tree Nut Allergy Panel with Reflex to Components

Test Code: 36766 

CPT Code(s): 86003 (x21), 82785

Clinical Significance: Childhood and Tree Nut Allergy Panel with Reflex to Components - Up to 90 percent of children with asthma have underlying allergies that trigger their asthma [1,2]. Many things like environmental and food elements can trigger allergic reactions in children. Specific IgE serological tests aid in the diagnosis of allergic disease. In this profile, when a whole allergen protein extract is found to be positive, the respective component panel, which uses individual recombinant or purified proteins, is automatically run. Component panels improve specificity, provide the clinician with more detailed information for assessing level of risk, and help target effective management.

1. Allen-Ramey F, et al. J Am Board Fam Pract 2005;18(5):434-439.
2. Host A, Halken S. Allergy 2000;55:600-608.

Includes: IgE allergy testing for:
Almond (f20)
Alternaria alternata (m6)
Brazil Nut (f18) IgE with Reflex to Component
Cashew Nut (f202) IgE with Reflex to Component
Cat Dander (e1) IgE with Reflex to Component Panel
Cladosporium herbarum (m2)
Cockroach (i6)
Codfish (f3)
Cow's Milk (f2) IgE with Reflex to Milk Component Panel
Dermatophagoides farinae (d2)
Dermatophagoides pteronyssinus (d1)
Dog Dander (e5) IgE with Reflex to Component Panel
Egg White (f1) IgE with Reflex to Egg Component Panel
Hazelnut (f17) IgE with Reflex to Component Panel
Macadamia Nut (rf345)
Mouse Urine Proteins (e72)
Peanut, Total with Reflex to Peanut Component Panel
Shrimp (f24)
Soybean (f14)
Walnut (f256) IgE with Reflex to Component Panel
Wheat (f4)

Immunoglobulin E

If Brazil Nut (f18) IgE is ≥0.10 kU/L, then Brazil Nut Component Ber e1 (f354) will be performed at an additional charge (CPT code(s): 86008).

If Cashew Nut (f202) IgE is ≥0.10 kU/L, then Cashew Nut Component Ana o3 (f443) will be performed at an additional charge (CPT code(s): 86008).

If Cat Dander (e1) IgE is ≥0.10 kU/L, then Cat Component Panel will be performed at an additional charge (CPT code(s): 86008 (x4)).
Cat Dander Component Panel includes Fel d 1 (e94) IgE, Fel d 2 (e220) IgE, Fel d 4 (e228) IgE, Fel d 7, and (e231) IgE.

If Cow's Milk (f2) IgE is ≥0.10 kU/L, then Milk Component Panel will be performed at an additional charge (CPT code(s): 86008 x3).
Milk Component Panel includes Alpha-lactalbumin (f76) IgE, Beta-lactoglobulin (f77) IgE, and Casein (f78) IgE.

If Dog Dander (e5) IgE is ≥0.10 kU/L, then Dog Component Panel will be performed at an additional charge (CPT code(s): 86008 (x6)).
Dog Dander Component Panel includes Can f 1 (e101) IgE, Can f 2 (e102) IgE, Can f 3 (e221) IgE, Can f 4 (e229) IgE, Can f 5 (e226) IgE, and Can f 6 (e230) IgE.

If Egg White (f1) IgE is ≥0.10 kU/L, then Egg Component Panel will be performed at an additional charge (CPT code(s): 86008 x2).
Egg Component Panel includes Ovalbumin (f232) IgE and Ovomucoid (f233) IgE.

If Hazelnut (f17) IgE is ≥0.10 kU/L, then Hazelnut Component Panel will be performed at an additional charge (CPT code(s): 86008 x4).
Hazelnut Component Panel includes Cor a1 (f428), Cor a8 (f425), Cor a9 (f440), and Cor a14 (f439).

If Peanut (f13) IgE is ≥0.10 kU/L, then Peanut Component Panel will be performed at an additional charge (CPT code(s): 86008 x6).
Peanut Component Panel includes Ara h 1 (f422), Ara h 2 (f423), Ara h 3 (f424), Ara h 6 (f447), Ara h 8 (f352), and Ara h 9 (f427).

If Walnut (f256) IgE is ≥0.10 kU/L, then Walnut Component Panel will be performed at an additional charge (CPT code(s): 86008 x2).
Walnut Component Panel includes rJug r1(f441) and rJug r3 (f442).

Methodology: Immunoassay (IA)

Alternative Name(s): Tree Nut Childhood Allergy, ImmunoCAP®