The American Medical Association (AMA) has issued updates to the Current Procedural Terminology (CPT®) codes to the 2027 edition of the CPT. Diagnostic Laboratory of Oklahoma (DLO) will implement these changes effective January 1, 2027.
These updates impact the billing of certain laboratory tests, including tests that may be ordered individually or as part of panels or profiles. The chart below outlines the affected tests and their corresponding CPT code changes.
For additional details, including reflex testing information, please refer to our Virtual Test Guide or the Quest Diagnostics Test Directory for a full comprehensive list of tests.
Download a PDF of the CPT Code Changes for 2027 Table
Click here to view the latest ICD-10 and CPT 2027 updates
Download Diagnosis Codes for Laboratory Orders
Download Aetna Office Links Update (2027)
| Order Code | Test Name | 2026 CPT Coding | 2027 CPT Coding |
|---|---|---|---|
| 18456 | Mycoplasma genitalium rRNA, NAAT with Reflex to Macrolide Resistance | 87563 with reflex to 87999 | 87563 with reflex to 87544 |
| 14319 | Glial Fibrillary Acidic Protein (GFAP) | 83520 | 82939 |
| 10120 | SureSwab® Advanced Vaginitis Plus, TMA | 81513, 87481 (x2), 87661, 87494 | 81513, 87479, 87494 |
| 10029 | SureSwab® Advanced Candida Vaginitis (CV)/Trichomonas vaginalis (TV), TMA | 87481 (x2), 87661 | 87479 |
| 10119 | SureSwab® Advanced Vaginitis, TMA | 81513, 87481 (x2), 87661 | 81513, 87479 |
| 39306 | Measles (Rubeola) Virus, Qualitative Real-Time PCR, Nasopharyngeal/Throat | 87798 | 87638 (effective 5/15/2026) |
We appreciate your continued support and value the opportunity to serve your laboratory testing needs. As CPT coding transitions to the 2027 AMA guidelines, DLO will make every reasonable effort, within our authority and according to federal and state policy, to assist you in navigating the updated codes applicable to our test offerings. Thank you for choosing DLO as your trusted laboratory partner!
Note: The CPT codes provided are based on current AMA guidelines and are offered for informational purposes only. Responsibility for accurate CPT® coding rests solely with the billing party. Please direct any coded-related questions to the payer being billed or contact DLO Billing by submitting a contact form with your inquiry.
