Test Name: Troponin I, High Sensitivity; former test name Troponin I *updated 03.02.2026
Alternative Name(s): Troponin HS, High Sensitivity, hsTnl
Test Code: 34693; former test code 59039 *updated 03.02.2026
CPT Code(s): 84484
Methodology: Chemiluminescent Microparticle Immunoassay (CMIA)
Clinical Significance: Troponin I is part of a protein complex which regulates the contraction of striated muscle. In acute coronary syndromes (ACS), high sensitivity assays can detect levels of cTnl within 3 hours after onset of chest pain. Cardiac troponin I reaches peak concentrations in approximately 8 to 28 hours and remains elevated for 3 to 10 days following MI. Cardiac troponin is the preferred biomarker for the detection of myocardial infarction based on sensitivity and tissue-specific compared to other available biomarkers of necrosis, including CK-MB, myoglobin and lactate dehydrogenase. When an increased value for cTnl is encountered in the absence of evidence of myocardial ischemia, other etiologies for cardiac damage should be considered. Elevated troponin levels may be indicative of myocardial injury associated with heart failure, renal failure, chronic renal disease, myocarditis, arrhythmias, pulmonary embolism, or other clinical conditions.
Supply: #T35 Light Green LiHep BD Vacutainer tube 4.5mL
Preferred Specimen: Plasma collected in Lithium Heparin
Preferred Volume:
- Male: 2.9 - 35 ng/L
- Female: 2.9 - 14 ng/L
Transport Container: Lithium Heparin Vacutainer
Transport Temperature: Refrigerated
SPECIAL INSTRUCTIONS: SEPARATE FROM CELLS WITHIN 2 HOURS OF COLLECTION
Specimen Stability:
- Room temperature :8 hours
- Refrigerated: 24 hours
- Frozen: Unacceptable
Rejection Criteria: Heat inactivated specimens, Pooled specimens, Grossly hemolyzed specimens, Specimens with obvious microbial contamination, Specimens with fungal growth, Frozen specimens
For additional supply or collection device information, please contact DLO's Customer Service at (800) 891-2917, option 2.
The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the Payor being billed.