OB/Gyn

Clone of BRCAvantage with Reflex to Breast Plus Panel

Breast Plus Panel without BRCA (TP53, STK11, PTEN, CDH1, PALB2)

Test Code: 92586

CPT Code(s): 81321, 81323, 81404, 81405 (x2), 81406 (x2), 81479

Clinical Significance: CDH1, PALB2, PTEN, STK11 and TP53 are tumor suppressor genes, where inherited mutations significantly increase breast cancer risk. Sequence analysis and deletion/duplication analysis of these five genes can explain an additional 3% to 4.5% of hereditary breast cancers.

BRCAvantage with Reflex to Breast Plus Panel

Test Code: 92573

CPT Code(s): 81162

Includes: If the Interpretation Summary is not one of the following three results: Positive for a known Pathogenic Mutation; Positive for a likely Pathogenic Mutation; Positive for a likely Pathogenic Mutation and a variant with unknown significance, then TP53, PTEN, CDH1, STK11, and PALB2 will be performed at an additional charge (CPT code(s) 81321, 81323, 81404, 81405 (x2), 81406 (x2), 81479).