Chlamydia/N. gonorrhoeae and T. vaginalis RNA, Qualitative, TMA
Test Code: 16492
CPT Code(s): 87494, 87661
Clinical Significance: To diagnose three sexually transmitted infections associated with vaginitis.
Includes: Chlamydia/Neisseria gonorrhoeae RNA, TMA, Urogenital, Trichomonas vaginalis RNA, Qualitative, TMA
Methodology: Transcription-Mediated Amplification (TMA)
Alternative name(s): Vaginosis discharge, leukhorrea, vaginal discharge, asymptomatic cervicitis
Supply: #A03 APTIMA® Vaginal (Multitest) Swab or #A01 Aptima Urine Tube or #A02 Aptima HOLOGIC Unisex Swab
- 1 vaginal swab in Aptima® Transport Tube or
- 1 endocervical swab in Aptima Transport Tube or
- 2 mL female urine in Aptima Transport Tube
Alternative Specimen(s): Female or male Urine (no preservatives): 2 mL of urine, specimen must be transferred into the Aptima Urine Transport Medium within 24 hours of collection and before being assayed.
Minimum volume: 1 vaginal swab • 1 endocervical swab • 2 mL urine
Collection instructions:
Vaginal swab: Follow instructions in the Aptima Multitest Collection Kit (orange label).
Endocervical swab: Follow instructions in the Aptima Unisex Swab Specimen Collection Kit (white label). In females, to ensure collection of cells infected with N. gonorrhoeae/C. trachomatis, columnar epithelial cells lining the endocervix should be obtained. Excess mucus should be removed prior to sampling.
Urine: Direct patient to provide a first-catch urine (a maximum of 20-30 mL of the initial urine stream) into a urine collection cup free of any preservatives. 2 mL of urine specimen must be transferred into the Aptima Specimen Transport Tube within 24 hours of collection and before being assayed. Use the tube provided in the urine specimen collection kit. The fluid (urine plus transport media) level in the urine transport tube must fall within the clear pane of the tube label.
Transport container: Aptima Transport Tube
Transport temperature: Room temperature
Specimen Stability:
Swab in Aptima Transport
Room temperature: 60 days
Refrigerated: 60 days
Frozen: 6 months
Urine in Aptima Transport
Room temperature: 30 days
Refrigerated: 30 days
Frozen: 6 months
Rejection Criteria:
- Transport tubes with 2 swabs
- Transport tubes with non-Aptima swabs
- Swab transport tubes with no swab
- Specimens in broken containers
- Swab submitted in viral transport media
- Urine samples where the fluid level is not between the black fill lines
- Pap vials
For additional supply or collection device information, please contact DLO's Customer Services at (800) 891-2917, option 2.
*The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.