FSH and LHMain Content
Test Code: 7137
Clinical Significance: FSH and LH are secreted by the anterior pituitary in response to gonadotropin-releasing hormone (GNRH) secreted by the hypothalamus. In both males and females, FSH and LH secretion is regulated by a balance of positive and negative feedback mechanisms involving the hypothalamic-pituitary axis, the reproductive organs, and the pituitary and sex steroid hormones. FSH and LH play a critical role in maintaining the normal function of the male and female reproductive systems. Abnormal FSH levels with corresponding increased or decreased levels of LH, estrogens, progesterone, and testosterone are associated with a number of pathological conditions. Increased FSH levels are associated with menopause and primary ovarian hypofunction in females and primary hypogonadism in males. Decreased levels of FSH are associated with primary ovarian hyper-function in females and primary hypergonadism in males. Normal or decreased levels of FSH are associated with polycystic ovary disease in females. In males, LH is also called interstitial cell-stimulating hormone (ICSH). Abnormal LH levels with corresponding increased or decreased levels of FSH, estrogens, progesterone, and testosterone are associated with a number of pathological conditions. Increased LH levels are associated with menopause, primary ovarian hypofunction, and polycystic ovary disease in females and primary hypo-gonadism in males. Decreased LH levels are associated with primary ovarian hyperfunction in females and primary hyper-gonadism in males.
Alternative Name(s): Follicle stimulating hormone and Luteinizing hormone; FSH/LH, Serum; FSH/LHS; Follicle stimulating hormone and Interstitial cell stimulating hormone
Supply: T01 - Red/Gray SST 8.5mL
Preferred Specimen: Serum
Preferred Volume: 2mL
Transport Container: Serum Separator Tube (SST)
Transport Temperature: Room Temperature
Specimen Stability: Room Temperature: 7 days
SPECIAL INSTRUCTIONS: For prepubertal children test codes 36087 (FSH, pediatrics) and 36086 (LH, pediatrics) are recommended
Rejection Criteria: Unlabeled, improperly labeled specimens; Specimens other than serume
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